SCREATE

Cell state · L2

MONO.CD16.hepatic_mac_like

2,426 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

Read trait, study and gene evidence reports for this population →

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Marker genes

APOC1, C1QA, C1QB, C1QC, CD14, CD163, CLEC10A, FOLR2, HLA-DMA, HLA-DQA1, LGALS2, LGMN, MS4A6A, RNASE6, SELENOP, VSIG4

Annotation genes

APOC1, CD163, FOLR2, VSIG4

Annotation rationales

CD163/VSIG4/FOLR2 plus C1Q reflect tolerogenic scavengers akin to Kupffer cells; APOC1/SELENOP handle lipid/redox stress.

Functional implications

Conduct complement control and iron/lipid scavenging in vascular beds (liver-biased), maintaining tolerance despite constant antigen exposure from portal blood.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.