Cell state · L2
MONO.CD14.repair_M2_like
2,857 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CTSB, DAB2, FABP5, GPNMB, LGMN, LYVE1, MS4A4A, RGS1, RNASE1, TREM2, VSIG4
Annotation genes
GPNMB, LGMN, LYVE1, MS4A4A, TREM2, VSIG4
Annotation rationales
TREM2/GPNMB/LGMN promote lipid-efferocytosis and matrix proteolysis; VSIG4 dampens complement; LYVE1 suggests vascular residency and tissue repair orientation.
Functional implications
Clear apoptotic bodies and lipid debris, encourage angiogenesis and scar remodeling, and suppress excessive complement to restore homeostasis.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.