Cell state · L2
MONO.CD14.cord_tolerance
2,293 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ADM, ATF3, DDIT4, DNAJB4, GADD45A, HSPA1B, ID1, JUN, NFKBIZ, NR4A1, TRIB1
Annotation genes
ADM, ATF3, DDIT4, JUN, NFKBIZ, NR4A1
Annotation rationales
NR4A1/ATF3/NFKBIZ/TRIB1 imprint a restrained TLR program typical of neonatal tolerance; DDIT4 shifts metabolism to stress resilience; ADM modulates vascular tone and leukocyte flow.
Functional implications
Provides controlled antimicrobial responses with minimal collateral damage, favoring resolution and tissue protection in perinatal/early-life immunity.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.