Cell state · L2
MAC.resident_repair.antigen_presenting
1,649 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CLEC10A, FCER1A, FCN1, HLA-DPA1, HLA-DPB1, HLA-DRA, HLA-DRB1, VSIR
Annotation genes
CLEC10A, FCER1A, HLA-DPB1, HLA-DRA
Annotation rationales
HLA-DR(A/B/DP) plus CLEC10A/FCER1A define potent antigen capture/presentation with Fc and C-type lectin pathways; VSIR contributes inhibitory signaling. Annotation genes indicate APCs tuned for controlled T-cell activation in healing tissue.
Functional implications
Sample local antigens, activate/regulate T cells to clear pathogens while preventing autoimmunity, and coordinate with stromal cells to keep repair on track through VSIR-mediated restraint.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.