SCREATE

Cell subtype · L1S

HEP.pericentral_lipoprotein

196 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

GLUL, CYP2E1, APOB, APOE, CYP3A4

Annotation genes

GLUL, CYP2E1, APOB

Annotation rationales

Pericentral lipoprotein hepatocytes occupy the low-oxygen central-vein zone and combine lipoprotein handling with xenobiotic and nitrogen metabolism.

Functional implications

They support lipid packaging and export, glutamine synthesis and zone-specific detoxification, while being sensitive to hypoxic and toxic injury.

More specific populations

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.