Cell subtype · L1S
HEP.canalicular_transport
18,746 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ABCB11, ABCB4, ABCC2, ATP8B1, ALB
Annotation genes
ABCB11, ABCB4, ABCC2
Annotation rationales
Canalicular-transport hepatocytes are polarized cells specialized for exporting bile acids, phospholipids and conjugated metabolites into bile canaliculi.
Functional implications
They drive bile formation, cholesterol disposal and hepatobiliary clearance while protecting the liver from toxic metabolite accumulation.
More specific populations
- HEP.canalicular_transport.baseline
- HEP.canalicular_transport.ductular_like_transition
- HEP.canalicular_transport.inflammatory
- HEP.canalicular_transport.injury_stress
- HEP.canalicular_transport.pericentral_like_hypoxia
- HEP.canalicular_transport.secretory_ERAD_UPR
- HEP.canalicular_transport.sterol_lipid_biosynthesis
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.