SCREATE

Cell state · L2

GRNLSA.stress_metabolic

325 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

ACTR3, CAPZA1, CDC42EP3, COTL1, CYTH4, ICAM1, PLEK, TNFAIP3

Annotation genes

CDC42EP3, CYTH4, ICAM1, TNFAIP3

Annotation rationales

ICAM1 sustains endothelial docking; CDC42EP3/CYTH4 remodel actin for crawling and phagosome dynamics; TNFAIP3 (A20) limits NF-κB-driven damage during surveillance.

Functional implications

Execute endothelial and interstitial patrol, capture opsonized targets swiftly, and keep inflammatory output tightly regulated to preserve tissue integrity.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.