Cell state · L2
GRNLSA.secretory_remodeling
831 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ALOX5AP, ARPC2, CAP1, CST7, CYBA, S100A11, S100A12, S100A6, TXN
Annotation genes
ALOX5AP, CST7, S100A12, TXN
Annotation rationales
ALOX5AP equips leukotriene synthesis for chemotaxis; CST7 restrains granule proteases until triggering; S100A12 flags high inflammatory readiness; TXN supports redox balance for oxidative bursts.
Functional implications
Rapidly release primary/secondary granules, generate ROS, and form NETs on cue, prioritizing extracellular bacterial and fungal neutralization with minimal lag time.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.