Cell state · L2
GRNLSA.p53_damage
297 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CMA1, COMMD2, COX8A, CSTB, CTSG, HPGD, HYAL3, IFITM1, IFITM3, MGST3, PTPRA, RWDD4, S100A4, SCOC
Annotation genes
CMA1, CTSG, HPGD, IFITM1, IFITM3
Annotation rationales
CMA1/CTSG stock granules; HPGD deactivates prostaglandins to control tone; IFITM1/3 mark baseline antiviral readiness—traits of quiescent, chymase-rich mast cells.
Functional implications
Provide sentinel storage of mediators and regulate vascular/ECM homeostasis; switch to effector mode upon IgE/PRR signals with minimal delay.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.