Cell state · L2
EPI.ileal_enterocyte_crypt.secretory_precursor
179 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ATOH1, CCL24, DLL1, DMPK, FAM174B, HES6, HPCAL1, KCNMA1, LINC00261, LRRC26, MB, RAB26, REP15, SELENOM, SPDEF, SPINK4, ST6NAC1, TFF3, TMEM61, WFDC2
Annotation genes
ATOH1, DLL1, SPDEF, TFF3
Annotation rationales
ATOH1 and SPDEF commit toward secretory lineages; DLL1 signals to neighbors via Notch to balance fates; TFF3 supports epithelial restitution. Vesicle-trafficking genes (RAB26/REP15) prime secretory routing.
Functional implications
Supplies progenitors for goblet/Paneth/tuft/enteroendocrine cells; coordinates local Notch signaling to maintain the absorptive–secretory ratio; contributes early restitution factors during crypt repair.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.