Cell state · L2
EPI.ileal_enterocyte_crypt.proliferative_G2M
461 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ASPM, BIRC5, CCNB1, CCNB2, CDC20, CDKN3, CENPF, CENPW, DLGAP5, FYB1, MIA, NUSAP1, PLK1, PTTG1, TESC, TPX2, TROAP, UBE2C
Annotation genes
BIRC5, CCNB1, CDC20, PLK1
Annotation rationales
A mitotic module (PLK1/CDC20/CCNB1) with survivin (BIRC5), centrosome/spindle factors (ASPM/NUSAP1/TPX2) typifies crypt cells in late cell cycle, driving rapid renewal.
Functional implications
Pushes progenitors through mitosis to sustain epithelial turnover; maintains villus supply of new enterocytes under baseline and after injury.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.