Cell state · L2
EPI.ileal_enterocyte_crypt.baseline
1,003 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CDX1, CDX2, LGALS4, OTC, REG1A, REG1B
Annotation genes
CDX1, CDX2, LGALS4, REG1A, REG1B
Annotation rationales
CDX1/2 establish intestinal epithelial identity; REG1A/1B encode restitution signals ready for rapid wound closure; LGALS4 shapes apical glycan interactions with the microbiota. Shared across crypt states, consistent with a poised, homeostatic crypt phenotype.
Functional implications
Maintains crypt identity and readiness for repair; supplies basal glycan–microbe tuning at the crypt mouth; serves as the foundation for specialized crypt programs (proliferation, bile handling, secretory priming).
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.