Cell subtype · L1S
EPI.esophageal_basal
904 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
KRT5, KRT14, TP63, KRT15, ITGA6
Annotation genes
TP63, KRT5, KRT14, ITGA6
Annotation rationales
Esophageal basal cells are proliferative keratinocytes anchored to the basement membrane of the stratified squamous mucosa. The TP63–KRT5–KRT14 program marks their basal progenitor identity.
Functional implications
They continuously replenish suprabasal layers and rapidly expand after injury to restore the esophageal barrier.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.