SCREATE

Cell state · L2

EC.venous.baseline

15,775 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

ACKR1, ADIRF, CCL14, CLU, HLA-DRB5, LY6E, TSPAN7

Annotation genes

ACKR1, CCL14, HLA-DRB5, LY6E

Annotation rationales

ACKR1/DARC marks post-capillary venules specialized in chemokine transcytosis. HLA-DRB5 highlights antigen-presenting capacity. LY6E is an ISG often present in tonic immune-interactive endothelia. CCL14 contributes to myeloid chemoattraction. This defines baseline venous ECs in immune trafficking hubs.

Functional implications

Chemokine-handling venous ECs that present/transport chemokines and support leukocyte adhesion/extravasation even at rest. They act as immune set-points, bridging circulation and tissue surveillance, maintaining readiness for immune recruitment in peripheral tissues.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.