Cell state · L2
EC.venous.adipose_lipid
1,788 cells in the full atlas (not the displayed sample).
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Marker genes
CA4, CD320, CD36, FABP4, FABP5, RBP7
Annotation genes
CA4, CD36, FABP4, RBP7
Annotation rationales
FABP4/5–CD36–RBP7 is the canonical fatty acid uptake/binding module enriched in adipose microvasculature. CA4 supports CO₂/HCO₃⁻ handling in metabolically active tissues. This signature reflects venous endothelium specialized for metabolic exchange in adipose depots.
Functional implications
Metabolic-specialized venous ECs that facilitate fatty acid trafficking into adipocytes and regulate CO₂ buffering in adipose-rich beds. They adapt circulation to nutrient flux, ensuring efficient FA mobilization and gas balance during feeding/fasting cycles, thereby coupling microvascular transport with adipose metabolism.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.