Cell state · L2
EC.arterial.metabolic
2,790 cells in the full atlas (not the displayed sample).
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Marker genes
COX7A1, ELOB, NDUFA3, ROMO1, RPL35, RPLP1, RPLP2, RPS14, RPS15, RPS28, SERF2, SRP14, TNNI3, UBL5, UQCR11, UQCRB, UQCRQ
Annotation genes
COX7A1, NDUFA3, UQCR11
Annotation rationales
ETC subunits (COX7A1/NDUFA3/UQCR11) plus ribosomal/translation genes indicate high ATP generation and protein turnover, suited for sustained shear sensing and junction renewal. ROMO1 flags ROS modulation within mitochondria, a byproduct of elevated OXPHOS.
Functional implications
Energy and proteome maintainers: supply ATP for eNOS/NO production, cytoskeletal remodeling, and continuous junctional/ glycocalyx renewal under arterial shear. Controlled ROS handling preserves signaling without oxidative damage, sustaining barrier complexity during chronic flow.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.