SCREATE

Cell state · L2

EC.arterial.ion_pump

778 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

Read trait, study and gene evidence reports for this population →

Explore this population in Cell Browser →

Marker genes

FXYD6

Annotation genes

FXYD6

Annotation rationales

FXYD6 modulates the Na⁺/K⁺-ATPase, tuning membrane potential, cell volume, and calcium handling that influence junctional stability and vasomotor responses, especially under fluctuating shear/ionic loads.

Functional implications

Electro-osmotic tuners: fine-adjust Na⁺/K⁺ pump activity to stabilize endothelial barrier and tone, preventing edema and preserving smooth muscle–endothelium signaling during rapid hemodynamic shifts.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.