Cell state · L2
EC.arterial.elastic
2,033 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ABI3BP, BGN, BMX, CLU, COL8A1, ELN, FBLIM1, FBLN2, FN1, GJA5, IGFBP3, LTC4S, MGP, PTGIS, SULF1
Annotation genes
ELN, GJA5, MGP, PTGIS, SULF1
Annotation rationales
ELN/FBLN2/COL8A1/FN1 encode an elastic, resilient ECM; GJA5 (Cx40) supports rapid electrotonic coupling across arterial endothelium; PTGIS produces prostacyclin (vasodilatory, anti-platelet); MGP inhibits calcification; SULF1 edits heparan sulfates to tune growth-factor gradients. Signature fits conduit/elastic artery endothelium.
Functional implications
Conduit-maintenance specialists: preserve elastic lamina integrity, provide prostacyclin to limit thrombosis/vasospasm, and prevent medial calcification. Fast gap-junction coupling synchronizes vasomotor responses along the arterial tree, ensuring smooth pressure transmission from heart to microcirculation.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.