Cell state · L2
ASPC.stem_like_progenitor
2,337 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
C1QTNF3, CD55, CD70, CLEC3B, DACT2, DEFB1, DKK1, EFHD1, FABP3, MFAP5, NTM, PCOLCE2, PROCR, WNT10B
Annotation genes
C1QTNF3, CD55, DKK1, PROCR, WNT10B
Annotation rationales
PROCR marks multipotent vascular-associated progenitors; WNT10B is anti-adipogenic while DKK1 tempers WNT, indicating a tunable stem-like module. C1QTNF3 (adipokine) and CD55 (complement regulation) situate them at an immune-aware niche interface.
Functional implications
Depot renewal and fate control. Preserve a self-renewing ASPC pool, calibrate WNT thresholds to decide adipogenic vs fibrogenic outcomes, and provide long-term regeneration capacity during cycles of weight gain/loss or injury.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.